Wednesday 11 September 2013

Beneftis of fish oil

BENEFITS OF FISH OIL


Everyone definitely heard of fish oil. When we mention about fish oil, the keyword that come into our mind is Omega 3. Omega 3 contains 2 important fatty acids, namely; eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Regular consumption of these healthy fats (of course with healthy lifestyle) can help to prevent chronic diseases that are link to the body’s inflammatory processes. Both EPA and DHA have shown wonderful anti-inflammatory properties.

Are you taking fish oil right? Are you in the right age to take fish oil?  We have customer who tell us that the reason she is not taking fish oil, is because she has not reach 40+ year old.

Here are 4 reasons why fish oil should be a regular part of your daily diet, even <40 years old:


1.       Protect your heart!
Fish oil has been shown to lower triglycerides (TG) level in your body. TG are a type of fat that acts as energy stores for the body. However, high level of TG in the body has been link to the development of heart disease.

2.       Enhances your brain
When I was young, our parents will tell us to eat more fish so that we can grow up smarter. It is indeed very true! Fish is always known as ‘brain food’, as DHA is the most abundant fatty acid in the brain. Without sufficient DHA, the brain tissue will start to deteriorate. Studies also have shown that diet rich in fish oil help to protect against cognitive decline.

3.       Better eyesight
Ongoing research reveals promising results in the effects of fish oil in delaying the progress of eye diseases such as macular degeneration and glaucoma.  Both of this disease are not curable and can cause blinded. Try to take note of the people surrounding you. Those who consume a lot of fish, might have better eye sight!

4.       Eases menstrual cramps
Research shows that fish oil can help alleviate menstrual cramps, due to its anti-inflammatory effect. In addition, the need for pain medication can be reduced or the dose can be lowered.

5.       Better skin
Fish oil also helps to moisturize your skin naturally. Fish oil also helps to balance up your hormone, which help to make your skin less oily. Fish oil also help to combat acne by reducing redness and puffiness of acne lesions.
  

Monday 12 August 2013

Omega 7 - The New Good Fat


Many people these days are familiar about the health benefits of Omega 3, 6 and 9. Have you heard of Omega 7 - the new good fat?

Before I proceed to Omega 7, let me make a short summary on Omega 3,6 and 9, so that we can understand omega 7 better.

Where can you find all this omega?

  • Omega 3, also known as alpha-linolenic acid is abundant in flaxseed and fish oils.
  • Omega 6, also known as linoleic acid can be found in borage and evening primrose oils.
  • Omega 9, also known as oleic acid is abundant in olive and avocade oils.

Both Omega 3 and 6 area essential fatty acids that are crucial for the brain, heart, and immune system. They cannot be synthesized by the human body and must be obtained from diet or supplements.

On the other hand, Omega 9 is non-essential fatty acid, which help to lower cholesterol levels and build up the immune system. It can be produced by the body, or obtained from food.

Omega 7 - The New Good Fat

Omega 7 is a non-essential fatty acid found predominantly in sea buckthorn oil and macadamia nuts. Omega 7 is also known as palmitoleic acid. Let me summarizes the main benefits below:

Skin, hair and nails
Omega 7 provides key building blocks for skin, hair and nails. It helps combat wrinkles, dryness, loss of skin elasticity, and other symptoms of malnourished or aging skin. It also helps skin function properly by supporting numerous skin functions, such as boosting collagen production, enhance skin ability to retain moisture, protect against sun damage, toxins, and environmental stress.

Weight management
Taken internally, omega 7 fatty acid signals the body to stop storing fat. This amazing compound also helps the body maintain insulin sensitivity and fight off the imbalances that can result in metabolic syndrome. Insulin sensitivity plays a major role in helping the body convert glucose into energy, rather than storing it as fat. Research shows that omega 7 imitates a hormone in the body that helps regulate systemic metabolic activity.

Cardiovascular health
The increased access to omega 7 will benefit the cardiovascular system. The positive benefits to cardiovascular health includes:
(1) reduce the amount of bad cholesterol traveling through your arteries
(2) help smooth their passage, which in turn helps artery walls stay strong and resistant to tearing.

Gastro-intestinal health
Omega 7 has a soothing and smoothing effect on all the body’s sensitive internal linings. Omega 7 helps to nourish and hydrate internal organs and combat stressors, including excessive stomach acid or chronic inflammation. The body needs this powerful fatty acid to plump up those sensitive linings, just like it uses them to plump thin, stretched skin cells. 

Conclusion
While we await the results of ongoing randomized trials on Omega 7, the data so far is promising. With a potential drug-like effect on our heart, pancreas and liver. Omega 7 have the potential to become a household name, much like Omega 3 were a bit longer than a decade ago.


Clinical References: 
  • Effect of dietary supplementation with sea buckthorn seed and pulp oils on the fatty composition of skin glycerophospholipids of patients with Atopic Dermatitis. Yang, B, et al., 2000, Jour Nutr BioChem, Vol. 11, 338-340. 
  • Anti-inflammatory activity of sea buckthorn (Hippophae rhamnoides) leaves. Ganju, L et al., 2005, Intr Immunopharm, Vol. 5, 1675-1684. 
  • Chronic administration of palmitoleic acid reduces insulin resistance and hepatic lipid accumulation in KK-Ay mice and genetic type 2 diabetes. Yang, et al., Lipids in Health and Disease, 2011, 10:120. 
  • Serum Lipid Effects of a High–Monounsaturated Fat Diet Based on Macadamia Nuts. Curb, J. et al., 2000, Arch Intern Med/Vol. 160. 
  • Lipoprotein composition and serum cholesterol ester fatty acids in nonwestern Melanesians. Lindeberg, S. et al., 1996, Lipids, Vol. 31, no. 2. 
  • Trans-Palmitoleic Acid, Metabolic Risk Factors, and New-Onset Diabetes in U.S. Adults. Mozaffarian, D. et al., Annals Intr Med, 2010, Vol. 153, no. 12. 
  • Sea buckthorn oils: Towards healthy mucous membranes. Erkkola, R. & Yang, B., 2003, AGROFood Industry, 53 (3). 


Sunday 11 August 2013

Benefits of carrot

Some facts about carrot:

  • Carrot comes from the Greek name 'karoton', which mean carotene?
  • Fats help the absorption of carotenoids into the blood by 1000% as carotenoids are fat soluble.
  • Carrots are the second most popular vegetables after potatoes.


Here are some of the benefits of carrot:
 
Improved Vision
The main compound is actually beta-carotene, which help for night vision and to protect against macular degeneration.

2.  Cancer Prevention
Studies have shown carrots reduce the risk of lung cancer, breast cancer and colon cancer. Researchers have just discovered falcarinol and falcarindiol which they feel cause the anticancer properties.
Falcarinol is a natural pesticide produced by the carrot that protects its roots from fungal diseases. Carrots are one of the only common sources of this compound. A study showed 1/3 lower cancer risk by carrot-eating mice.

Anti-Aging
The high level of beta-carotene acts as an antioxidant to cell damage done to the body through regular metabolism.

Healthy Glowing Skin (from the inside)
It also contains vitamin A which act as an antioxidant to protect the skin from sun damage. Vitamin A prevents premature wrinkling, acne, dry skin, pigmentation, blemishes, and uneven skin tone. Some people even use it as a facial mask, by combining it with honey.


Powerful Antiseptic
It can be used to prevent infection.

Prevent Heart Disease
High in carotenoids can  help to lower the risk of heart disease.Regular consumption of carrots also reduces cholesterol levels because the soluble fibers in carrots bind with bile acids.

Healthy Teeth and Gums
Marvellous isn't it? Carrots clean your teeth and mouth by scarping off plaque and food particles just like toothbrush or toothpaste. Carrots stimulate gums and trigger a lot of saliva, which being alkaline, which help to prevent cavity-forming bacteria.

Saturday 10 August 2013

An Overview of Honey


I had read a very interesting articles reviewing honey. I wish to share the summary of part of the review article.
 
Honey is a natural substance produced when the nectar and sweet deposits from plants are gathered, modified, and stored in the honeycombs by honeybees. Honey can be classified as floral and non floral honey. Floral honey is made by the nectar collected from flowers. Non floral honey is made by bees that extracts sugars from living tissues of plants or fruits or scavenge the excretions of insects.  Honey’s colour, aroma, flavour, density, and physical and chemical properties depend on the flowers used by bees.

The nutrition values and profiles vary according to the composition of honey. Carbohydrates constitute about 95-97% of the dry weight of honey. Water is quantitatively the second most important component of honey. Only honey with less than 80% water can be stored with little or no risk fermentation.  The protein content is roughly 0.5% of which are mainly enzymes and free amino acids.

Fructose and glucose are the most predominant sugars present in honey. Approximately 18 essential and non essential amino acids are present in honey.  Proline is the primary amino acid and lysine being the second most prevalent. Vitamins and minerals such as thiamin, riboflavin, niacin, and calcium in honey depend on it’s botanical and geographical origin.

Honey is found to be suitable sweetener in fermented milk product without inhibiting the growth of common bacteria like Streptococcus thermophiles, Lactobacillus acidophilus, Lactobacillus delbbruekii, and Bifidobacterium bifidum which are important for maintaining a healthy gastrointestinal tract. Honey acts as a prebiotic in probiotic cultures.

Honey’s carbohydrates are easily to be digested and quickly transported into blood and can be utilized for energy requirement by human body. Hence, honey is particularly recommended for children and sportsmen. 
















Friday 5 July 2013

Fish Oil Triglycerides vs Ethyl Esters

From my experience as a retail pharmacist, fish oil is one of the most sought after item. Do you know that the product that you buy might not be of pharmaceutical quality. Although a product label may say “Fish Oil”, the chances are the product is not an oil at all, rather it is an alternate lipid class called a fatty acid ethyl ester (FAEE) or just EE for short. The authentic fish oil has a chemical structure known as a triglyceride (TG).

This post is to help our reader to differentiate between ethyl ester and triglyceride fish oil.


What are triglycerides (TG)?

The National Academy of Sciences defines fats and oils as “complex organic molecules that are formed by combining three fatty acids with one molecule of glycerol”. Triglycerides contain three fatty acids (i.e. EPA and DHA) esterified (bonded) to a glycerol backbone. TGs are the natural molecular form that make up virtually all fats and oils in both animal and plants species. The omega-3 fats present in fish are almost exclusively TGs. Free fatty acids are rapidly oxidized. Therefore, TG structure offers greater stability to the fatty acids and prevents breakdown and oxidation.

What are ethyl esters (EE)?

Fatty acid ethyl esters are a class of lipids that are derived by reacting free fatty acids with ethanol (alcohol). This process is known as trans-esterification. The industry make of use this EE form, as they can use fractional distilation (molecular distilation) to selectively concentrate EPA and DHA to levels greater than found naturally in fish. 

This EE form of fish oil is wrongly markets as fish oil..

Are all fish oil concentrates ethyl esters?

Majority of fish oil concentrates sold globally are EPA and DHA EE concentrates. A small percentage of fish oil concentrates on the market are natural TGs.

It is possible to convert the fatty acids back to TGs using food grade enzymes, through a process called glycerolysis. However, it will easily add 30-40% to the final product cost.

Is there any difference in the absorption and metabolism of natural triglycerides vs. ethyl esters

To make it simple, just remember that fish oil need to be digested by pancreatic lipase enzyme. EE form will be different, because its fatty acid-ethanol bond is 50 times more resistant to pancreatic lipase enzyme. 

Another thing is EE form need to be reconverted back to TG form before tranported in the blod. TG resynthesis will be delayed without any free glycerol in the body. This delay could cause an increase in free fatty acids and subsequent oxidation of those free fatty acids

There are many studies that favour both TG and EE form, but the overall evidence suggests that TG fish oils are better absorbed in comparison to EE. Natural TG fish oil results in 50 % more plasma EPA and DHA after absorption in comparison to EE oils. One of the factors for the poor bioavailability of EE is a much greater resistance to digestive enzymes.

How about other countries?

Some countries (e.g. Australia) have gone as far as banning the sale of EEs. Other countries such as the US, Canada, and the UK allow the sale of the EE form and furthermore do not require any additionally labeling. These supplements are therefore often incorrectly labeled as “Fish Oil” and pose a risk to those who must avoid ingestion of alcohol.